BiOptimizers is a premium supplement company founded by former professional athletes Wade Lightheart and Matt Gallant, focusing on optimizing health through superior formulations, particularly in the areas of digestion, gut health, and cognitive function. The brand is known for its uncompromising focus on high-potency, science-backed ingredients, often featuring multi-component formulas like their signature products.
The core philosophy revolves around achieving a "biologically optimized state" by addressing foundational health issues, with a strong emphasis on the body's ability to absorb and utilize nutrients.
Detailed Review: BiOptimizers Supplements
Brand Strengths
Science-Backed Formulations: BiOptimizers is committed to using clinically-researched ingredients in effective doses. Many products are proprietary, unique blends.
Focus on Absorption: A major theme across their product line is enhancing nutrient absorption, evidenced by the inclusion of digestive enzymes (Masszymes) and HCL (HCL Breakthrough).
Quality & Purity: Products are typically non-GMO, gluten-free, soy-free, and often dairy-free, catering to various dietary needs. They also emphasize third-party testing for purity and potency.
Specialized Blends: They don't just offer single-ingredient supplements; they create comprehensive formulas (e.g., eight forms of magnesium in one product).
Areas for Consideration
Cost: As a premium brand with high-potency, complex formulas, their products are generally priced higher than competitors.
Potency for Beginners: Some formulas, particularly the digestive aids, are very potent and may require a careful ramp-up period for individuals new to supplements or with sensitive systems.
Top 10 Best-Selling BiOptimizers Products
BiOptimizers' most popular products consistently center around improving digestion, sleep, stress management, and brain function.
# | Product Name | Primary Function | Key Ingredients/Benefits |
1. | Magnesium Breakthrough 🧠💤 | Sleep, Stress & Muscle Recovery | Combines seven to eight forms of magnesium (e.g., Malate, Glycinate, Citrate, Orotate) to cover a broad range of biological needs, supporting relaxation and muscle function. |
2. | Masszymes 🦠 | Advanced Digestive Enzymes | A powerful, high-potency enzyme blend (Protease, Amylase, Lipase, etc.) designed to break down protein, carbs, and fats to maximize nutrient absorption and reduce bloating/gas. |
3. | P3-OM 🦠 | Proteolytic Probiotic | A patented, freeze-dried probiotic strain (Lactobacillus plantarum OM) that is designed to be proteolytic (breaks down protein) and is highly effective at multiplying in the gut. |
4. | Mushroom Breakthrough - Chocolicious 🍄 | Cognition, Energy & Immunity | A powder blend of four functional mushroom extracts (Lion's Mane, Cordyceps, Reishi, Chaga) combined with collagen for brain health, energy, and skin support, with a pleasant chocolate flavor. |
5. | HCL Breakthrough 💊 | Stomach Acid Support | Contains Betaine HCL and digestive enzymes to help optimize stomach acid levels, which is crucial for breaking down protein and absorbing minerals like B12 and iron. |
6. | Microbiome Breakthrough 🦠 | Pre-, Pro-, and Postbiotics | A comprehensive synbiotic formula designed to feed beneficial gut bacteria (prebiotics), introduce them (probiotics), and support the gut lining (postbiotics). |
7. | Cognibiotics 🧠 | Brain & Gut Axis | A nootropic formula that combines 17 probiotic strains with herbs traditionally used to support mood, memory, and cognitive speed. |
8. | Herbal Power Flush 🌿 | Intestinal Cleansing | A blend of herbs designed to promote healthy bowel movements and cleanse the colon, often used as part of a detox protocol. |
9. | Stress Guardian 😌 | Adrenal & Stress Relief | A formula containing adaptogens and calming compounds (like L-Theanine) to support the body's response to stress and cortisol balance. |
10. | Kapex 💊 | Fat Digestion & Metabolism | A specialized enzyme formula containing high amounts of lipase to support the digestion of fats, particularly useful for those on a high-fat, Ketogenic, or Paleo diet. |
Deep Dive: Flagship Products
Magnesium Breakthrough (Top Seller)
The Problem it Solves: Magnesium deficiency is common and affects everything from sleep quality to muscle function and stress response.
Unique Selling Point: Most magnesium supplements only contain one or two forms. Magnesium Breakthrough offers a complex of seven to eight different forms (Malate for muscle soreness, Glycinate for sleep, Citrate for bowel regularity, etc.) to ensure comprehensive absorption and benefit across various biological pathways.
Masszymes (Digestion Core)
The Problem it Solves: Poor digestion leads to malabsorption, bloating, and fatigue.
Unique Selling Point: Marketed as a "best-in-class" digestive enzyme blend, it features an extremely high protease content (for protein digestion), along with all other essential enzymes. The goal is to maximize the breakdown of food to ensure the body extracts the maximum nutritional value.
P3-OM (Probiotic Power)
The Problem it Solves: Standard probiotics often contain strains that don't effectively survive stomach acid or colonize the gut.
Unique Selling Point: P3-OM is based on a single, potent, third-party-tested strain (Lactobacillus plantarum OM). Its key feature is its proteolytic nature, meaning it actively helps break down protein and is designed to eliminate undesirable organisms in the gut while proliferating.
Mushroom Breakthrough - Chocolicious (Cognitive & Immunity)
The Problem it Solves: Getting a consistent, effective dose of functional mushrooms and collagen often involves multiple products or unpleasant tastes.
Unique Selling Point: This product blends highly concentrated extracts of Lion's Mane, Chaga, Cordyceps, and Reishi (known for neurogenesis, immunity, and stress reduction) with Marine and Bovine Collagen. The "Chocolicious" flavor (often sweetened with Monk Fruit) makes it highly palatable and easy to mix into coffee or smoothies. It is promoted as a daily ritual for enhanced focus and overall vitality.
HCL Breakthrough (The Absorption Catalyst)
The Problem it Solves: Low stomach acid (Hypochlorhydria) is a common, yet often overlooked, cause of poor digestion, leading to indigestion, gas, and poor mineral absorption.
Unique Selling Point: Unlike enzyme-only products, this supplement provides Betaine HCL to directly increase stomach acid levels, which is the foundational step for proper digestion. It's paired with enzymes to maximize the breakdown of food once the correct pH is established.
Overall Verdict
BiOptimizers stands out in the crowded supplement market by targeting the foundational aspects of health: digestion and absorption. By ensuring the body can properly process food and utilize key nutrients (like magnesium), the brand delivers products that often lead to noticeable improvements in energy, sleep, mood, and cognitive function.
While the price point is higher, the complexity and potency of their multi-formulation products like Magnesium Breakthrough and Masszymes often justify the cost for consumers seeking best-in-class results and comprehensive solutions rather than basic, single-ingredient supplements. They are a top choice for biohackers, athletes, and anyone serious about optimizing their internal health.


